You probably have noticed that your Wine windows don't have the same font than your Mac, right? That's because Windows use Tahoma, while Macs use the Helvetica Neue Family. Considering that the default Helvetica Neue was too thin in my tests, I'm suggesting the use of Helvetica Neue Bold with a bigger LogPixels to match the size of Tahoma.
Helvetica Neue winecfg
(I recommend opening the images in two different tabs to compare)
What do you think? Should we make that an option, do it all the time or just forget it?